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Another effect is that some products weren't developed at the same speed because R&D was focused on Covid drugs. In single-use processing, there's a direct link to drug launches, and Sartorius was impacted the most since they gained the largest shares. After this situation, some original suppliers tried to regain business with package deals. Big players like Danaher have significant negotiation power, especially with resins, and they try to bundle things for procurement. Customers are currently looking for cost savings, so some business returned to original players, not all, but some. You have the safety stock situation, and some delays in new drugs.
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Additionally, competition increased. During Covid, everyone wanted to join the market. Distributors turned into integrators and assemblers, and many companies emerged, building clean rooms for assemblies. Companies also entered customer processes they wouldn't have before. For example, in filtration, a high-margin market, there were three big players, Millipore, Pall, and Sartorius. For the customers, there was no need to add a fourth player. When doing RFQs, they got the best prices, and there is also the additional burden of managing more players. But during Covid, you couldn't get polyethylene filters, so they were forced to validate other customers, such as Meissner, and now these products are validated into the process and their pricing is under further pressure.
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Cytiva and Pall, another Danaher brand, are giants and by far the number one. They are true end-to-end providers, with the advantage of bundling a lot with their chromatography business, which is very profitable. This gives them leverage to push other technologies. Cytiva is the absolute leader in systems, with others trailing far behind. This enables them to push harder on new technologies. Once they finish integration, which typically takes time and involves some loss due to personnel changes, their engine becomes a formidable force. They are probably the toughest competition in the field.
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